Host subspecific viral strains in European house mice: Murine cytomegalovirus in the Eastern (Mus musculus musculus) and Western house mouse (Mus musculus domesticus)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F18%3A00492343" target="_blank" >RIV/68081766:_____/18:00492343 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/18:00103722
Result on the web
<a href="http://dx.doi.org/10.1016/j.virol.2018.05.023" target="_blank" >http://dx.doi.org/10.1016/j.virol.2018.05.023</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.virol.2018.05.023" target="_blank" >10.1016/j.virol.2018.05.023</a>
Alternative languages
Result language
angličtina
Original language name
Host subspecific viral strains in European house mice: Murine cytomegalovirus in the Eastern (Mus musculus musculus) and Western house mouse (Mus musculus domesticus)
Original language description
Murine cytomegalovirus (MCMV) has been reported from house mice (Mus musculus) worldwide, but only recently from Eastern house mice (M. m. musculus), of particular interest because they form a semi-permeable species barrier in Europe with Western house mice, M. in. domesticus. Here we report genome sequences of EastMCMV (from Eastern mice), and set these in the context of MCMV genomes from genus Mus hosts. We show EastMCMV and WestMCMV are genetically distinct. Phylogeny splitting analyses show a genome wide (94%) pattern consistent with no West-East introgression, the major exception (3.8%) being a genome-terminal region of duplicated genes involved in host immune system evasion. As expected from its function, this is a region of maintenance of ancestral polymorphism: The lack of clear splitting signal cannot be interpreted as evidence of introgression. The EastMCMV genome sequences reported here can therefore serve as a well-described resource for exploration of murid MCMV diversity.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
<a href="/en/project/GA14-35009S" target="_blank" >GA14-35009S: Quantifying viral gene capture, and the host’s response, during passage across a species barrier: Murine cytomegalovirus in a house mouse hybrid zone.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Virology
ISSN
0042-6822
e-ISSN
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Volume of the periodical
521
Issue of the periodical within the volume
August
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
92-98
UT code for WoS article
000439956400010
EID of the result in the Scopus database
2-s2.0-85048574353