Evolutionary history of Pneumocystis fungi in their African rodent hosts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F19%3A00507280" target="_blank" >RIV/68081766:_____/19:00507280 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/19:00112246
Result on the web
<a href="http://dx.doi.org/10.1016/j.meegid.2019.103934" target="_blank" >http://dx.doi.org/10.1016/j.meegid.2019.103934</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.meegid.2019.103934" target="_blank" >10.1016/j.meegid.2019.103934</a>
Alternative languages
Result language
angličtina
Original language name
Evolutionary history of Pneumocystis fungi in their African rodent hosts
Original language description
Pneumocystis is a genus of parasitic fungi infecting lung tissues in a wide range of mammal species, displaying a strong host specificity and patterns of co-speciation with their hosts. However, a recent study on Asiatic murids challenged these patterns reporting several Pneumocystis lineages/species shared by different host species or even genera in the Rattini and Murini tribes. Here we screened lung samples of 27 species of African rodents from five families for the presence of Pneumocystis DNA. Using reconstructed multi-locus phylogenies of both hosts and parasites, we tested the hypothesis of their co-evolution. We found that Pneumocystis is widespread in African rodents, detected in all but seven screened host species, with species-level prevalence ranging from 5.9 to 100%. Several host species carry pairs of highly divergent Pneumocystis lineages/species. The retrieved co-phylogenetic signal was highly significant (p = .0017). We found multiple co-speciations, sorting events and two host-shift events, which occurred between Murinae and Deomyinae hosts. Comparison of genetic distances suggests higher substitution rates for Pneumocystis relative to the rodent hosts on neutral loci and slower rates on selected ones. We discuss life-history traits and population dynamics factors which could explain the observed results.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Infection, Genetics and Evolution
ISSN
1567-1348
e-ISSN
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Volume of the periodical
75
Issue of the periodical within the volume
November
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
10
Pages from-to
103934
UT code for WoS article
000495408600005
EID of the result in the Scopus database
2-s2.0-85068380107