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The opportunistic protist, Giardia intestinalis, occurs in gut-healthy humans in a high-income country

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F23%3A00578523" target="_blank" >RIV/68081766:_____/23:00578523 - isvavai.cz</a>

  • Alternative codes found

    RIV/60076658:12310/23:43907120

  • Result on the web

    <a href="https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2270077" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2270077</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/22221751.2023.2270077" target="_blank" >10.1080/22221751.2023.2270077</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The opportunistic protist, Giardia intestinalis, occurs in gut-healthy humans in a high-income country

  • Original language description

    Giardia intestinalis, a cosmopolitan gastrointestinal protist, is detected mainly in patients with clinical giardiasis in high-income countries. In contrast, there is very little information on the presence of Giardia in asymptomatic individuals. Therefore, the aim of this study was to determine the presence and prevalence of Giardia in gut-healthy volunteers in the Czech Republic and to perform a comparative evaluation of different diagnostic methods, since Giardia diagnostics is complicated. Our results confirmed that the qPCR method is the most sensitive method for detecting Giardia and revealed a prevalence of 7% (22/296) in asymptomatic individuals. In most cases, the colonization intensity ranged from 10-1-101. A conventional PCR protocol targeting the TPI gene was used to identify the assemblages. However, this protocol had limited sensitivity for Giardia amplification, effectively detecting colonization above an intensity of 104. In addition, Giardia was detected in 19% of the animals, which were closely associated with the study participants. However, due to methodological limitations, zoonotic transmission could not be clearly confirmed. Notably, contact with animals proved to be the only factor that had a significant impact on the incidence of Giardia in gut-healthy humans.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30302 - Epidemiology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Emerging Microbes & Infections

  • ISSN

    2222-1751

  • e-ISSN

    2222-1751

  • Volume of the periodical

    12

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    10

  • Pages from-to

    2270077

  • UT code for WoS article

    001099095300001

  • EID of the result in the Scopus database

    2-s2.0-85175245819