Specific anti-SVCV antibodies in hybrids of common carp (Cyprinus carpio) and gibel carp (Carassius gibelio) reflect heterosis advantage and genetic breakdown

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F24%3A00587922" target="_blank" >RIV/68081766:_____/24:00587922 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14310/24:00136899

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0044848624007816?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0044848624007816?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.aquaculture.2024.741320" target="_blank" >10.1016/j.aquaculture.2024.741320</a>

Result language

angličtina

Original language name

Specific anti-SVCV antibodies in hybrids of common carp (Cyprinus carpio) and gibel carp (Carassius gibelio) reflect heterosis advantage and genetic breakdown

Original language description

Spring viraemia of carp virus (SVCV) is a disease with a serious economic impact on the farming of cyprinid fish. High susceptibility to SVCV has been documented mostly in common carp (Cyprinus carpio), whilst gibel carp (Carassius gibelio) is a weakly susceptible species. Specific anti-SVCV antibodies were analyzed in pure lines of common carp and gibel carp, and various generations of F1 and post-F1 hybrids. Specifically, we focused on anti-SVCV antibodies in weakly susceptible F1 hybrids and highly infected backcross and F2 hybrids, hypothesizing that the level of anti-SVCV antibodies will reflect heterosis advantage in F1 generations and hybrid breakdown in post-F1 generations. Backcross generations with common carp exhibited the most frequently symptomatic infections, followed by pure common carp. The high capacity of susceptible common carp to produce anti-SVCV antibodies was reported, whilst gibel carp expressed almost undetectable levels of anti-SVCV antibodies. We found the very good capacity of F1 hybrids to produce anti-SVCV antibodies, suggesting heterosis advantage. In contrast, we revealed different patterns of anti-SVCV antibodies production between maternal backcrosses (having parents with the same mtDNA – here, gibel carp) and paternal backcrosses (having parents with different mtDNA, i.e., resulting from reciprocal crosses of F1 hybrids with gibel carp mtDNA and pure common carp). Whilst both maternal backcross generations and the F2 generation of hybrids tended to produce low anti-SVCV antibodies, both paternal backcross generations expressed levels of anti SVCV-antibodies similar to those of highly susceptible common carp. The low capacity to produce anti-SVCV antibodies in F2 hybrids may be interpreted as a potential consequence of genetic disruption. However, the different capacity to induce an adaptive response in paternal hybrids and maternal hybrids (with mtDNA C. gibelio) may be interpreted as potential compensation for the cyto-nuclear breakdown hypothesized for paternal hybrids when coping with viral infection. Alternatively, the genetic background of hybrid fish, i.e. a combination of the genes of highly susceptible common carp and of less susceptible gibel carp in the hybrid genome may be responsible for this pattern.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40301 - Veterinary science

Project

<a href="/en/project/GA19-10088S" target="_blank" >GA19-10088S: Genetic disruption in interspecific hybrids of cyprinid fish: its impact on vigour-associated traits, immunity and parasite load</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Aquaculture

ISSN

0044-8486

e-ISSN

1873-5622

Volume of the periodical

593

Issue of the periodical within the volume

December

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

10

Pages from-to

741320

UT code for WoS article

001275773300001

EID of the result in the Scopus database

2-s2.0-85198829260