Neurotropic tick-borne flavivirus in Alpine chamois (Rupicapra rupicapra rupicapra), Austria, 2017, Italy, 2023
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F25%3A00605595" target="_blank" >RIV/68081766:_____/25:00605595 - isvavai.cz</a>
Result on the web
<a href="https://www.mdpi.com/1999-4915/17/1/122" target="_blank" >https://www.mdpi.com/1999-4915/17/1/122</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/v17010122" target="_blank" >10.3390/v17010122</a>
Alternative languages
Result language
angličtina
Original language name
Neurotropic tick-borne flavivirus in Alpine chamois (Rupicapra rupicapra rupicapra), Austria, 2017, Italy, 2023
Original language description
The European subtype of tick-borne encephalitis virus (TBEV-Eur, species Orthoflavivirus encephalitidis, family Flaviviridae) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. Here, we report a tick-borne flavivirus isolated from Alpine chamois (Rupicapra rupicapra rupicapra) with encephalitis and attached ticks, present over a wide area in the Alps. Cases were detected in 2017 in Salzburg, Austria, and 2023 in Lombardy and Piedmont, Italy. The virus strains exhibit 94.8-97.3% nucleotide identities to each other and are more closely related to Louping ill viruses (LIV, Orthoflavivirus loupingi, 90-92% identities) than to TBEV-Eur (less than 88%). The chamois-derived virus strains, tentatively termed 'Alpine chamois encephalitis virus', form a well-supported independent genetic clade with Spanish goat encephalitis virus, clearly separated from other LIV. This supports its designation as a new virus subtype with the proposed shared taxonomic name 'Spanish goat and Alpine chamois encephalitis virus subtype' within the species Orthoflavivirus loupingi. The zoonotic potential of this newly identified virus subtype as well as its host range in other animal species including farm animals needs to be further investigated.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
<a href="/en/project/NU21-05-00143" target="_blank" >NU21-05-00143: Hidden zoonoses - uncovering new pathogenic agents from wildlife</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Viruses
ISSN
1999-4915
e-ISSN
1999-4915
Volume of the periodical
17
Issue of the periodical within the volume
1
Country of publishing house
CH - SWITZERLAND
Number of pages
16
Pages from-to
122
UT code for WoS article
001404522600001
EID of the result in the Scopus database
2-s2.0-85216076653