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Acrylonitrile exposure: the effect on p53 and p21WAF1 protein levels in the blood plasma of occupationally exposed workers and in vitro in human diploid lung fibroblasts.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F02%3A19023019" target="_blank" >RIV/68378041:_____/02:19023019 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Acrylonitrile exposure: the effect on p53 and p21WAF1 protein levels in the blood plasma of occupationally exposed workers and in vitro in human diploid lung fibroblasts.

  • Original language description

    The study on the effect of ACN exposure on the expression of p53 and p21WAF1 proteins in vitro and in vivo. The study group consisted of 49 subjects exposed to ACN in the petrochemical industry. Subjects living in the same area but not working in this factory were used as controls. No significant differences in either p53, or p21WAF1 levels between the exposed and control groups were found. Also no effect of GSTM1 and GSTT1 genotypes was observed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    DN - Environmental impact on health

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/SI%2F340%2F1%2F97" target="_blank" >SI/340/1/97: Impact of environmental pollution on the human health in the Teplice region - Teplice Program II</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2002

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Mutation Research. Genetic Toxicology and Environmental Mutagenesis

  • ISSN

    0027-5107

  • e-ISSN

  • Volume of the periodical

    N/A

  • Issue of the periodical within the volume

    517

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    12

  • Pages from-to

    239-250

  • UT code for WoS article

  • EID of the result in the Scopus database