Acrylonitrile exposure: the effect on p53 and p21WAF1 protein levels in the blood plasma of occupationally exposed workers and in vitro in human diploid lung fibroblasts.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F02%3A19023019" target="_blank" >RIV/68378041:_____/02:19023019 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Acrylonitrile exposure: the effect on p53 and p21WAF1 protein levels in the blood plasma of occupationally exposed workers and in vitro in human diploid lung fibroblasts.
Original language description
The study on the effect of ACN exposure on the expression of p53 and p21WAF1 proteins in vitro and in vivo. The study group consisted of 49 subjects exposed to ACN in the petrochemical industry. Subjects living in the same area but not working in this factory were used as controls. No significant differences in either p53, or p21WAF1 levels between the exposed and control groups were found. Also no effect of GSTM1 and GSTT1 genotypes was observed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
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Result continuities
Project
<a href="/en/project/SI%2F340%2F1%2F97" target="_blank" >SI/340/1/97: Impact of environmental pollution on the human health in the Teplice region - Teplice Program II</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2002
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
ISSN
0027-5107
e-ISSN
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Volume of the periodical
N/A
Issue of the periodical within the volume
517
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
12
Pages from-to
239-250
UT code for WoS article
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EID of the result in the Scopus database
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