Clinical implementation of 4-dihydroxyborylphenylalanine synthesised by an asymetric pathway.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F03%3A19033015" target="_blank" >RIV/68378041:_____/03:19033015 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Clinical implementation of 4-dihydroxyborylphenylalanine synthesised by an asymetric pathway.
Original language description
Boron neutron capture therapy (BNCT) is an experimental therapeutic modality combining a boron pharmaceutical with neutron irradiation. 4-Dihydroxyborylphenylalanine (L-BPA) synthesised via the novel pathway was developed to be boron containing pharmaceutical in the first series of clinical trials. Prior to starting clinical trials the acute toxicity of L-BPA was studied in male albino Sprague- Dawley rats. In accordance with earlier studies no adverse effect were observed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Pharmaceutical Sciences. Pharmaceutical Sciences
ISSN
0928-0987
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
N/A
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
9
Pages from-to
155-163
UT code for WoS article
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EID of the result in the Scopus database
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