Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F10%3A00340197" target="_blank" >RIV/68378041:_____/10:00340197 - isvavai.cz</a>
Alternative codes found
RIV/00027162:_____/10:#0000628
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution
Original language description
The impact of PAHs and VOCs on sperm quality in a group of city policemen in Prague during winter season (high exposure) compared to spring season (low exposure) were studied. Polymorphisms in metabolic genes (CYP1A1, EPHX1, GSTM1, GSTP1, GSTT1), folic acid metabolism genes (MTR, MTHFR) and DNA repair genes (XRCC1, XPD6, XPD23, hOGG1) were evaluated as potential modifiers of associations between air pollution exposure and changes in sperm quality. No significant differences were found in any standard semen parameters between the sampling periods except for vitality of sperms.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1QS500390506" target="_blank" >1QS500390506: Impact of environmental and genetic factors on men fertility</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mutation Research
ISSN
0027-5107
e-ISSN
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Volume of the periodical
683
Issue of the periodical within the volume
1-2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
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UT code for WoS article
000273845500002
EID of the result in the Scopus database
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