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Biomarkers of exposure and effect ? interpretation for human risk

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F11%3A00363581" target="_blank" >RIV/68378041:_____/11:00363581 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Biomarkers of exposure and effect ? interpretation for human risk

  • Original language description

    The effect of exposure to carcinogenic PAHs adsorbed onto respirable air particles on DNA adducts and chromosomal aberrations was repeatedly studied in groups of policemen and bus drivers from Prague, Czech Republic. Personal exposure was evaluated usingpersonal samplers during working shifts. DNA adducts were analyzed in lymphocytes by the 32P-postlabeling assay and chromosomal aberrations by conventional cytogenetic analysis and by fluorescent in situ hybridization (FISH). The studies suggest that the environmental exposure of nonsmokers to concentrations higher than 1 ng B[a]P/m3 represents a risk to DNA damage, as indicated by an increase in DNA adducts and in the genomic frequency of translocations determined by FISH.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    DN - Environmental impact on health

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Air Quality, Atmosphere and Health (AQAH)

  • ISSN

    1873-9318

  • e-ISSN

  • Volume of the periodical

    4

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    9

  • Pages from-to

    161-167

  • UT code for WoS article

  • EID of the result in the Scopus database