Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F11%3A00368699" target="_blank" >RIV/68378041:_____/11:00368699 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1038/cddis.2011.98" target="_blank" >http://dx.doi.org/10.1038/cddis.2011.98</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/cddis.2011.98" target="_blank" >10.1038/cddis.2011.98</a>

Result language
angličtina
Original language name
Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord
Original language description
Here, we have performed a preliminary mapping of serotonergic processes and serotonin-lA (5-HT(1A)) receptors in thoracic and lumbar segments of the human spinal cord. 5-HT profiles in human spinal cord are present in the ventral horn, surrounding motoneurons, and also contact their presumptive dendrites at lumbar level. 5-HT(1A) receptors are present in the same area, but are more densely expressed at lumbar level. These findings pave the way for local specific therapies involving cellular and/or pharmacological tools targeting the serotonergic system.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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