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Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F12%3A00373891" target="_blank" >RIV/68378041:_____/12:00373891 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1093/hmg/ddr523" target="_blank" >http://dx.doi.org/10.1093/hmg/ddr523</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1093/hmg/ddr523" target="_blank" >10.1093/hmg/ddr523</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13

  • Original language description

    Previously we have identified two genomic regions in which pairs of tagging-single nucleotide polymorphisms (tagSNPs) are associated with disease in genome-wide association studies of colorectal cancer. Simple genotyping of additional sample sets at theoriginal tagSNPs didn?t show expected results, we therefore undertook more detailed analyses, using imputation, logistic regression, genealogical analysis using the GENECLUSTER program, and haplotype analysis. We revealed new facts about the situation in1q41 and 12q13.13 regions and found strong evidence for candidate functional variants.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Human Molecular Genetics

  • ISSN

    0964-6906

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    13

  • Pages from-to

    934-946

  • UT code for WoS article

    000299792800018

  • EID of the result in the Scopus database