Immunohistochemical expression of matrix metalloproteinases in the rabbit corneal epithelium upon UVA and UVB irradiation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F12%3A00377641" target="_blank" >RIV/68378041:_____/12:00377641 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.acthis.2011.10.004" target="_blank" >http://dx.doi.org/10.1016/j.acthis.2011.10.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.acthis.2011.10.004" target="_blank" >10.1016/j.acthis.2011.10.004</a>

Result language
angličtina
Original language name
Immunohistochemical expression of matrix metalloproteinases in the rabbit corneal epithelium upon UVA and UVB irradiation
Original language description
Matrix metalloproteinases (MMPs) are proteolytic enzymes involved in tissue remodeling and wound healing. These enzymes degrade and also synthesize components of the extracellular matrix. Overexpression of MMPs results in excessive extracellular matrix degradation and tissue destruction. In the cornea, destructive processes may lead to scarring and loss of vision. In this study, the effect of UVA and UVB irradiation on expression of matrix metalloproteinases in the rabbit corneal epithelium was examinated.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FF - ENT (ie. ear, nose, throat), ophthalmology, dentistry
OECD FORD branch
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Project
<a href="/en/project/GPP302%2F10%2FP155" target="_blank" >GPP302/10/P155: Matrix metalloproteinases in seriously damaged cornea and after its reconstruction by stem cell transplantation.</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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