Immunocytochemical profiles of inferior colliculus neurons in the rat and their changes with aging

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F12%3A00385992" target="_blank" >RIV/68378041:_____/12:00385992 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3389/fncir.2012.00068" target="_blank" >http://dx.doi.org/10.3389/fncir.2012.00068</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fncir.2012.00068" target="_blank" >10.3389/fncir.2012.00068</a>

Result language
angličtina
Original language name
Immunocytochemical profiles of inferior colliculus neurons in the rat and their changes with aging
Original language description
A review summarizing distribution and age-related changes of GABAergic neurons and neurons expressing calcium binding proteins (CBPs ? parvalbumin, calbindin, calretinin). The expression of glutamate decarboxylase (GAD) (a key enzyme for GABA synthesis)and calcium binding proteins in the neuron of the rat IC undergoes significant decline with aging. Similar age-related changes in GAD and CBPs expression are present in the IC of two rat strains with differently preserved inner ear function up to late senescence (Long-Evans and Fischer 344), which suggests that these changes do not depend exclusively on peripheral deafferentation but are, at least partially, of central origin.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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