Reduced gene expression levels after chronic exposure to high concentrations of air pollutants
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F15%3A00451370" target="_blank" >RIV/68378041:_____/15:00451370 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.mrfmmm.2015.08.001" target="_blank" >http://dx.doi.org/10.1016/j.mrfmmm.2015.08.001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.mrfmmm.2015.08.001" target="_blank" >10.1016/j.mrfmmm.2015.08.001</a>
Alternative languages
Result language
angličtina
Original language name
Reduced gene expression levels after chronic exposure to high concentrations of air pollutants
Original language description
We analyzed the ability of particulate matter (PM) and chemicals adsorbed onto it to induce diverse gene expression profiles in subjects living in two regions of the Czech Republic differing in levels and sources of the air pollution. Gene expression profiles differed by locations and seasons. Despite lower concentrations of air pollutants, a higher number of differentially expressed genes and affected KEGG pathways was found in subjects from less polluted region. This observation suggests that chronicexposure to air pollution may result in reduced gene expression response with possible negative health consequences.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
ISSN
0027-5107
e-ISSN
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Volume of the periodical
780
Issue of the periodical within the volume
oct
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
11
Pages from-to
60-70
UT code for WoS article
000362306000007
EID of the result in the Scopus database
2-s2.0-84940049917