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Reduced gene expression levels after chronic exposure to high concentrations of air pollutants

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F15%3A00451370" target="_blank" >RIV/68378041:_____/15:00451370 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.mrfmmm.2015.08.001" target="_blank" >http://dx.doi.org/10.1016/j.mrfmmm.2015.08.001</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.mrfmmm.2015.08.001" target="_blank" >10.1016/j.mrfmmm.2015.08.001</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Reduced gene expression levels after chronic exposure to high concentrations of air pollutants

  • Original language description

    We analyzed the ability of particulate matter (PM) and chemicals adsorbed onto it to induce diverse gene expression profiles in subjects living in two regions of the Czech Republic differing in levels and sources of the air pollution. Gene expression profiles differed by locations and seasons. Despite lower concentrations of air pollutants, a higher number of differentially expressed genes and affected KEGG pathways was found in subjects from less polluted region. This observation suggests that chronicexposure to air pollution may result in reduced gene expression response with possible negative health consequences.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    DN - Environmental impact on health

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

  • ISSN

    0027-5107

  • e-ISSN

  • Volume of the periodical

    780

  • Issue of the periodical within the volume

    oct

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    11

  • Pages from-to

    60-70

  • UT code for WoS article

    000362306000007

  • EID of the result in the Scopus database

    2-s2.0-84940049917