The role of mesenchymal stromal cells in spinal cord injury
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00472194" target="_blank" >RIV/68378041:_____/17:00472194 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The role of mesenchymal stromal cells in spinal cord injury
Original language description
Spinal cord injury (SCI) is one of the most devastating diseases that affects patients and their families for the rest of their lives. Among many treatments being developed for SCI, the placement of different types of grafts embedded with cell populations into areas of damage has been one of the most commonly usednregenerative approaches ,attracting scientists and physicians for the last 15 years. Stem/stromal cells are able to secrete a large repertoire of signaling molecules, including anti-inflammatory cytokines and growth factors, which may modulate the inhibitory environment of SCI while increasing trophic support to the resident cells. The chapter describes the pathology of spinal cord injury, the use of mesenchymal stromal cells derived from different sources in the treatment of SCI and their potential modifications and manipulations to reinforce their paracrine effect on neural tissue regeneration. n
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/LO1309" target="_blank" >LO1309: Cell Therapy and Tissue Repair</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
The Biology and Therapeutic Applications of Mesenchymal Cells
ISBN
978-1-118-90751-1
Number of pages of the result
16
Pages from-to
714-729
Number of pages of the book
1048
Publisher name
Wiley-Blackwell
Place of publication
Oxford
UT code for WoS chapter
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