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The role of mesenchymal stromal cells in spinal cord injury

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00472194" target="_blank" >RIV/68378041:_____/17:00472194 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The role of mesenchymal stromal cells in spinal cord injury

  • Original language description

    Spinal cord injury (SCI) is one of the most devastating diseases that affects patients and their families for the rest of their lives. Among many treatments being developed for SCI, the placement of different types of grafts embedded with cell populations into areas of damage has been one of the most commonly usednregenerative approaches ,attracting scientists and physicians for the last 15 years. Stem/stromal cells are able to secrete a large repertoire of signaling molecules, including anti-inflammatory cytokines and growth factors, which may modulate the inhibitory environment of SCI while increasing trophic support to the resident cells. The chapter describes the pathology of spinal cord injury, the use of mesenchymal stromal cells derived from different sources in the treatment of SCI and their potential modifications and manipulations to reinforce their paracrine effect on neural tissue regeneration. n

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    30103 - Neurosciences (including psychophysiology)

Result continuities

  • Project

    <a href="/en/project/LO1309" target="_blank" >LO1309: Cell Therapy and Tissue Repair</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    The Biology and Therapeutic Applications of Mesenchymal Cells

  • ISBN

    978-1-118-90751-1

  • Number of pages of the result

    16

  • Pages from-to

    714-729

  • Number of pages of the book

    1048

  • Publisher name

    Wiley-Blackwell

  • Place of publication

    Oxford

  • UT code for WoS chapter