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Opioids, the Immune System and Stem Cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00491809" target="_blank" >RIV/68378041:_____/17:00491809 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Opioids, the Immune System and Stem Cells

  • Original language description

    Opioid drugs are therapeutically used to relieve a severe pain. However, the use of opioids have numerous side effects. One of these effects is a decreased and impaired tissue healing observed after opioid administration or in opioid addicts. In this review we summarized the effects of morphine and other opioids on cells of the immune system and on various types of stem cells. Both immune and stem cells possess opioid receptors and their functions can be modified by opioid drugs. We conclude that the deleterious effects of opioid drugs on stem cells and cells of the immune system could be the reason for impaired healing observed after administration of opioids.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

    <a href="/en/project/LO1309" target="_blank" >LO1309: Cell Therapy and Tissue Repair</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Nanomaterials in Biomedical research

  • ISBN

    978-80-906655-5-2

  • Number of pages of the result

    4

  • Pages from-to

    134-137

  • Number of pages of the book

    140

  • Publisher name

    Proxima Tisk, s.r.o.

  • Place of publication

    Praha 3

  • UT code for WoS chapter