A Short Overview of the Methods Frequently Used in Nanotoxicology

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F18%3A00499208" target="_blank" >RIV/68378041:_____/18:00499208 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
A Short Overview of the Methods Frequently Used in Nanotoxicology
Original language description
The particles of nanoscale are widespread. Manufactured nanoparticles can be found in food, cosmetics, clothes, medications, as well as secondary in the environment (air, water, soil). They are widely used in many areas because of their specific properties which may differ from those exhibited by their bulk forms. While these properties are unique, they may also cause unexpected effects on organisms and the environment. Therefore in compliance with the application of precautionary principle every engineered nanoparticle should undergo the safety assessment: 1) comprehensive physico-chemical characterisation, 2) evaluation of toxic effects by biological methods. Screening of toxic effects of nanomaterials, both engineered and environmental (originating from both human activity such as wood and coal combustion, industrial production, engine emissions etc., and natural processes such as volcanic activity) on human health includes the characterization of nanoparticles, analysis of cytotoxicity, genotoxicity or oxidative stress primarily using models of human cell lines. Methods investigating the impact of environmental or engineered NPs on the environment are not included in this short overview.
Czech name
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Czech description
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Project
<a href="/en/project/LO1508" target="_blank" >LO1508: Genomics and proteomics in the study of mechanisms of biological effects of produced nanoparticles</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Nanostructures in Biomedicine: Their Regenerative and toxic properties
ISBN
978-80-906655-7-6
Number of pages of the result
8
Pages from-to
4-11
Number of pages of the book
198
Publisher name
Proxima Tisk, s.r.o.
Place of publication
Praha 3
UT code for WoS chapter
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