Dynamic creep properties of a novel nanofiber hernia mesh in abdominal wall repair

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F19%3A00518443" target="_blank" >RIV/68378041:_____/19:00518443 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/19:00338926 RIV/00216208:11510/19:10400250 RIV/00064203:_____/19:10400250 RIV/00216208:11130/19:10400250
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs10029-019-01940-w" target="_blank" >https://link.springer.com/article/10.1007%2Fs10029-019-01940-w</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10029-019-01940-w" target="_blank" >10.1007/s10029-019-01940-w</a>

Result language
angličtina
Original language name
Dynamic creep properties of a novel nanofiber hernia mesh in abdominal wall repair
Original language description
PurposeIncisional hernia is the most common complication following abdominal surgery. While mesh repair is common, none of the current meshes mimic the physiology of the abdominal wall. This study compares suture only repair with polypropylene mesh and a prototype of a novel implant (poly-epsilon-caprolactone nanofibers) and their influence on the physiology of an abdominal wall in an animal model.Methods27 Chinchilla rabbits were divided into six groups based on the type of the implant. Midline abdominal incision was repaired using one of the compared materials with suture alone serving as the control. 6 weeks post-surgery animals were killed and their explanted abdominal wall subjected to biomechanical testing.ResultsBoth-hysteresis and maximum strength curves showed high elasticity and strength in groups where the novel implant was used. Polypropylene mesh proved as stiff and fragile compared to other groups.ConclusionPoly-epsilon-caprolactone nanofiber scaffold is able to improve the dynamic properties of healing fascia with no loss of maximum tensile strength when compared to polypropylene mesh in an animal model.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10610 - Biophysics

Project
<a href="/en/project/NV17-32285A" target="_blank" >NV17-32285A: Functionalized nanofibers for prevention of incisional hernia formation</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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