EXPOSURE TO COPPER OXIDE NANOPARTICLES: BIOLOGICAL IMPACTS

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F19%3A00523420" target="_blank" >RIV/68378041:_____/19:00523420 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
EXPOSURE TO COPPER OXIDE NANOPARTICLES: BIOLOGICAL IMPACTS
Original language description
Copper (Cu) is a biogenic element that plays an important role in many biological processes. Cu is also used in various industrial products and its nanosized form has antibacterial and antiviral properties. Cu nanoparticles (NPs) are further applied in industry, chemistry and electronic devices. When compared with other metal oxide NPs, Cu NPs are less commonly used. However, the potential of copper oxide NPs (CuO NPs) to induce cytotoxicity and DNA damage in vitro was higher than that of other tested NPs. Despite this fact, studies on CuO NPs toxicity are relatively scarce and their effects on human health have never been investigated. In vitro tests in model cell lines showed the ability of CuO NPs to cause oxidative stress, but induction of apoptosis and cell cycle arrest were also observed. In animal studies, inflammatory responses in lungs were most common, but some studies revealed damage to other organs, including the brain. Considering toxicity of CuO NPs and the fact that these NPs are routinely manufactured and used in various products, more research is needed to elucidate mechanisms of their negative health effects in humans.
Czech name
—
Czech description
—

Project
<a href="/en/project/LO1508" target="_blank" >LO1508: Genomics and proteomics in the study of mechanisms of biological effects of produced nanoparticles</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
NANOCON 2018 - Conference Proceedings, 10th Anniversary International Conference on Nanomaterials - Research and Application
ISBN
978-808729489-5
ISSN
—
e-ISSN
—
Number of pages
6
Pages from-to
537-542
Publisher name
Tanger Ltd.
Place of publication
Ostrava
Event location
Brno
Event date
Oct 17, 2018
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
000513131900093

Similar results(10)