NG2 cells and their neurogenic potential
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F20%3A00539679" target="_blank" >RIV/68378041:_____/20:00539679 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S1471489219301158?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S1471489219301158?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.coph.2019.11.005" target="_blank" >10.1016/j.coph.2019.11.005</a>
Alternative languages
Result language
angličtina
Original language name
NG2 cells and their neurogenic potential
Original language description
NG2 cells, which comprise a cycling population of glial cells, appear in the early phases of development and are present in the adult central nervous system. When a specific subpopulation of NG2 cells give rise to myelinating oligodendrocytes, they are also termed as oligodendrocyte precursor cells. Considering their capacity to proliferate and differentiate into other cellular types, their fate has been extensively investigated in several genetically modified mice. It is generally accepted that NG2 cells are restricted to the oligodendrocyte lineage, but numerous reports describe their differentiation into astrocytes or even neurons. Here, we summarize studies that can prove and also disprove possible neurogenesis from NG2 cells in the different regions of the brain and spinal cord, with the main emphasis on the developmental stages and pathological conditions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/GA17-04034S" target="_blank" >GA17-04034S: Principal signaling pathways regulating NG2 glia proliferation and differentiation following brain injuries</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Current Opinion in Pharmacology
ISSN
1471-4892
e-ISSN
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Volume of the periodical
50
Issue of the periodical within the volume
SI
Country of publishing house
GB - UNITED KINGDOM
Number of pages
8
Pages from-to
53-60
UT code for WoS article
000564622400009
EID of the result in the Scopus database
2-s2.0-85076671669