Frequency of Leiden Mutation in Newborns with Birth Weight below 1500 g
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F22%3A00567282" target="_blank" >RIV/68378041:_____/22:00567282 - isvavai.cz</a>
Alternative codes found
RIV/60076658:12110/22:43904496 RIV/71226401:_____/22:N0100653
Result on the web
<a href="https://www.mdpi.com/2227-9032/10/5/865" target="_blank" >https://www.mdpi.com/2227-9032/10/5/865</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/healthcare10050865" target="_blank" >10.3390/healthcare10050865</a>
Alternative languages
Result language
angličtina
Original language name
Frequency of Leiden Mutation in Newborns with Birth Weight below 1500 g
Original language description
It has been hypothesized that fetal prematurity or Intrauterine Growth Restriction (IUGR) could be related to the presence of factor V of Leiden mutation. This mutation is associated with a higher incidence of pregnancy difficulties that can result in preterm birth. The frequency of Leiden mutation was investigated in the group of newborns with a low birth weight below 1500 g over a six-year period from 2015 to 2020. During this period, 339 newborns were tested, of which 42 newborns with V Leiden mutation (12.4%) were detected. The average of its occurrence frequency in the Czech population was determined as 5.0% based on published studies. In our research, the occurrence of the V Leiden mutation was found significantly higher in newborns under 1500 g. At the same time, we did not demonstrate an increased frequency of births at lower gestational weeks, lower birth weight, or an association with sex in newborns with a positive diagnosis of the Leiden V factor.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
<a href="/en/project/EF16_019%2F0000798" target="_blank" >EF16_019/0000798: Healthy Aging in Industrial Environment</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
HEALTHCARE-BASEL
ISSN
2227-9032
e-ISSN
2227-9032
Volume of the periodical
10
Issue of the periodical within the volume
5
Country of publishing house
CH - SWITZERLAND
Number of pages
6
Pages from-to
865
UT code for WoS article
000801241400001
EID of the result in the Scopus database
2-s2.0-85130118985