The Role of miR-20 in Health and Disease of the Central Nervous System
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F22%3A00568840" target="_blank" >RIV/68378041:_____/22:00568840 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/22:10443812
Result on the web
<a href="https://www.mdpi.com/2073-4409/11/9/1525" target="_blank" >https://www.mdpi.com/2073-4409/11/9/1525</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/cells11091525" target="_blank" >10.3390/cells11091525</a>
Alternative languages
Result language
angličtina
Original language name
The Role of miR-20 in Health and Disease of the Central Nervous System
Original language description
Current understanding of the mechanisms underlying central nervous system (CNS) injury is limited, and traditional therapeutic methods lack a molecular approach either to prevent acute phase or secondary damage, or to support restorative mechanisms in the nervous tissue. microRNAs (miRNAs) are endogenous, non-coding RNA molecules that have recently been discovered as fundamental and post-transcriptional regulators of gene expression. The capacity of microRNAs to regulate the cell state and function through post-transcriptionally silencing hundreds of genes are being acknowledged as an important factor in the pathophysiology of both acute and chronic CNS injuries. In this study, we have summarized the knowledge concerning the pathophysiology of several neurological disorders, and the role of most canonical miRNAs in their development. We have focused on the miR-20, the miR-17 similar to 92 family to which miR-20 belongs, and their function in the normal development and disease of the CNS.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cells
ISSN
2073-4409
e-ISSN
2073-4409
Volume of the periodical
11
Issue of the periodical within the volume
9
Country of publishing house
CH - SWITZERLAND
Number of pages
22
Pages from-to
1525
UT code for WoS article
000794498300001
EID of the result in the Scopus database
2-s2.0-85129680161