Differences in auditory temporal processing in the left and right auditory cortices of the rat

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F23%3A00580358" target="_blank" >RIV/68378041:_____/23:00580358 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21730/23:00364275 RIV/00216208:11120/23:43925137

Result on the web

<a href="https://www.sciencedirect.com/science/article/abs/pii/S0378595523000205?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0378595523000205?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.heares.2023.108708" target="_blank" >10.1016/j.heares.2023.108708</a>

Result language

angličtina

Original language name

Differences in auditory temporal processing in the left and right auditory cortices of the rat

Original language description

In the present study, we examined hemispheric differences in the representation and processing of tem-porally structured auditory stimuli. Neuronal responses evoked by sinusoidally frequency modulated (FM) tones, frequency sweeps, amplitude modulated (AM) tones and noise, click trains with constant inter-click intervals and natural vocalizations were recorded from the left (LAC) and right (RAC) auditory cortices in adult (4-6 months old) anaesthetized F344 rats. Using vector strength, modulation-transfer functions, van Rossum distances, or direction-selectivity index, representation and processing of structured audi-tory stimuli were compared in the LAC and the RAC. The RAC generally tended to exhibit a higher abil-ity to synchronize with the stimulus, a higher reproducibility of responses, and a higher proportion of direction-selective units. The LAC, on the other hand, mostly had higher relative response magnitudes in the modulation transfer functions. Importantly, the hemispheric differences were dependent on the type of the stimulus and there was also a significant inter-individual variability. Our findings indicate that neural coding in the RAC is based more on timing of action potentials (temporal code), while the LAC uses more the response magnitudes (rate code). It is thus necessary to distinguish between the type of the neural code and the stimulus feature it encodes and reconsider the simple opinion about dominance of the LAC for temporal processing, as it may not hold in general for all types of temporally structured stimuli.(c) 2023 Published by Elsevier B.V.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/LTAIN19201" target="_blank" >LTAIN19201: Processing of complex acoustical signals including vocalizations in inhibitory circuits of the central auditory system in mice models of autism and different types of sensorineural hearing loss.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Hearing Research

ISSN

0378-5955

e-ISSN

1878-5891

Volume of the periodical

430

Issue of the periodical within the volume

feb

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

9

Pages from-to

108708

UT code for WoS article

000963976800001

EID of the result in the Scopus database

2-s2.0-85147333941