Characterization and bioactivity of β-tricalcium phosphate powder sol-gel coatings on titanium substrates

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F25%3A00639597" target="_blank" >RIV/68378041:_____/25:00639597 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21220/25:00385459 RIV/60076658:12520/25:43910079
Result on the web
<a href="https://link.springer.com/article/10.1007/s10971-025-06918-y" target="_blank" >https://link.springer.com/article/10.1007/s10971-025-06918-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10971-025-06918-y" target="_blank" >10.1007/s10971-025-06918-y</a>

Result language
angličtina
Original language name
Characterization and bioactivity of β-tricalcium phosphate powder sol-gel coatings on titanium substrates
Original language description
The proliferation, differentiation or viability of cells on a bioactive surface such as ß-tricalcium phosphate (ß-TCP) is a key aspect of regenerative medicine and biomaterials research. In this study, a sol-gel solution specifically developed for biomaterial applications was used, into which crystalline ß-tricalcium phosphate (ß-TCP) powder was added at various concentrations. This approach differs from conventional methods where ß-TCP is synthesized directly within the sol–gel matrix. The direct incorporation of powder into the base sol allows for better control over particle distribution and size, influencing the morphology, mechanical properties, and biological activity of coatings applied to titanium substrates. The surfaces were characterized in terms of changes in roughness, wettability, and mechanical parameters. Biological tests with the MG63 cell line showed increased cell proliferation and adhesion, particularly during the first 48 h of cultivation, confirming the bioactive effect of the added ß-TCP powder. These results suggest the potential of this approach for developing bioactive coatings on titanium implants with improved osseointegration and stability.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20506 - Coating and films

Project
<a href="/en/project/LM2023050" target="_blank" >LM2023050: National Infrastructure for Biological and Medical Imaging</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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