The nuclear orphan receptor TR4 promotes proliferation of myeloid progenitor cells.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F01%3A23010444" target="_blank" >RIV/68378050:_____/01:23010444 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The nuclear orphan receptor TR4 promotes proliferation of myeloid progenitor cells.
Original language description
Nuclear receptors are key regulators in cell proliferation, differentiation and development. We demonstrate that the nuclear orphan receptor TR4 is expressed in hematopoietic cells and promotes proliferation of myeloid progenitors. Cells represent promyelocytes. We also demonstrate that the growth promoting activity of TR4 is not exclusively dependent onits binding to DNA. In conclusion, the orphan receptor TR4 as an important regulator of myeloid progenitor cell proliferation and development.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2001
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cell Growth and Differentiation
ISSN
1044-9523
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
N/A
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
563-572
UT code for WoS article
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EID of the result in the Scopus database
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