bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F02%3A23010491" target="_blank" >RIV/68378050:_____/02:23010491 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

bFGF signaling and v-Myb cooperate in sustained growth of primitive erythroid progenitors.

Original language description

The development of red blood cells from progenitors requires the interplay of specific extracellular factors and intracellular regulators. We show that cooperation of basic fibroblast growth factor (bFGF) with transcriptional regulators - mybproteins, represents an important factor for determining erythroid lineage choice and sustained proliferation of early erythroid cells. These findings unravel a so far unidentified link between extracellular signaling and Myb in hematopoietic cells.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Oncogene

ISSN

0950-9232

e-ISSN

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Volume of the periodical

21

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

400-410

UT code for WoS article

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EID of the result in the Scopus database

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