All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F07%3A00053521" target="_blank" >RIV/68378050:_____/07:00053521 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5

  • Original language description

    The activation of Wnt/beta-catenin signaling in the embryonic mouse telencephalon results in the up-regulation of Sp5 gene. The repression activity of R1 domain of Sp5 is mediated through direct interaction with a transcriptional corepressor mSin3a. Sp5transcription factor mediates the downstream responses to Wnt/beta-catenin signaling by directly repressing Sp1 target genes.

  • Czech name

    Snížená regulace signálu Wnt cílových genů Sp1 transkripčním represorem Sp5

  • Czech description

    Aktivace Wnt/beta-cateninové signální dráhy v myším embryonickém teleocephalonu reguluje expresi genu Sp5. Represorová aktivita domény R1 faktoru Sp5 je zprostředkována přímou interakcí s transkripčním korepresorem mSin3a. Transkripční faktor Sp5 převádísignál vedený do dráhy Wnt/beta-cateninu tím, že přímo reprimuje cílové geny Sp1.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Biological Chemistry

  • ISSN

    0021-9258

  • e-ISSN

  • Volume of the periodical

    282

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

    1225-1237

  • UT code for WoS article

  • EID of the result in the Scopus database