Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F11%3A00372311" target="_blank" >RIV/68378050:_____/11:00372311 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.3410/B3-10" target="_blank" >http://dx.doi.org/10.3410/B3-10</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3410/B3-10" target="_blank" >10.3410/B3-10</a>

Result language

angličtina

Original language name

Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer

Original language description

Dysregulation of the cell cycle is the underlying mechanism of neoplasia. Healthy cells prevent propagation of DNA mutations to progeny by activation of cellular checkpoints, which allows time for DNA repair. On the other hand, activation of the DNA damage response is also the general principle of many current cancer treatments. Thus, recent advances in understanding how checkpoints in the cell cycle work at the molecular level open the door to new approaches to antitumor therapy.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

F1000 biology reports

ISSN

1757-594X

e-ISSN

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Volume of the periodical

3

Issue of the periodical within the volume

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Country of publishing house

GB - UNITED KINGDOM

Number of pages

5

Pages from-to

"e10"

UT code for WoS article

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EID of the result in the Scopus database

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