Endogenous lentivirus in Malayan colugo (Galeopterus variegatus), a close relative of primates

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F14%3A00441030" target="_blank" >RIV/68378050:_____/14:00441030 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1186/s12977-014-0084-x" target="_blank" >http://dx.doi.org/10.1186/s12977-014-0084-x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s12977-014-0084-x" target="_blank" >10.1186/s12977-014-0084-x</a>

Result language

angličtina

Original language name

Endogenous lentivirus in Malayan colugo (Galeopterus variegatus), a close relative of primates

Original language description

Background: A significant fraction of mammalian genomes is composed of endogenous retroviral (ERV) sequences that are formed by germline infiltration of various retroviruses. In contrast to other retroviral genera, lentiviruses only rarely form ERV copies. We performed a computational search aimed at identification of novel endogenous lentiviruses in vertebrate genomes.Findings: Using the in silico strategy, we have screened 104 publicly available vertebrate genomes for the presence of endogenous lentivirus sequences. In addition to the previously described cases, the search revealed the presence of endogenous lentivirus in the genome of Malayan colugo (Galeopterus variegatus). At least three complete copies of this virus, denoted ELVgv, were detectedin the colugo genome, and approximately one hundred solo LTR sequences. The assembled consensus sequence of ELVgv had typical lentivirus genome organization including three predicted accessory genes. Phylogenetic analysis placed this viru

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

<a href="/en/project/LK11215" target="_blank" >LK11215: Regulation of active endogenous retroviruses in the mammalian genome</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Retrovirology

ISSN

1742-4690

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

84

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

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UT code for WoS article

000344509200001

EID of the result in the Scopus database

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