All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Development of 5 ' LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F16%3A00471925" target="_blank" >RIV/68378050:_____/16:00471925 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388963:_____/16:00472257 RIV/00216208:11110/16:10323674 RIV/00216208:11310/16:10323674 RIV/00216208:11120/16:43911073 and 2 more

  • Result on the web

    <a href="http://dx.doi.org/10.1186/s13148-016-0185-6" target="_blank" >http://dx.doi.org/10.1186/s13148-016-0185-6</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1186/s13148-016-0185-6" target="_blank" >10.1186/s13148-016-0185-6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Development of 5 ' LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals

  • Original language description

    Background: Human immunodeficiency virus type 1 (HIV-1) latency represents the major barrier to virus eradication in infected individuals because cells harboring latent HIV-1 provirus are not affected by current antiretroviral therapy (ART). We previously demonstrated that DNA methylation of HIV-1 long terminal repeat (5' LTR) restricts HIV-1 reactivation and, together with chromatin conformation, represents an important mechanism of HIV-1 latency maintenance. Here, we explored the new issue of temporal development of DNA methylation in latent HIV-1 5' LTR.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP304%2F12%2F1736" target="_blank" >GAP304/12/1736: Development of CpG methylation of HIV-1 promoter and its stabilizing effect on the latent provirus reservoir: longitudinal study in patients</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2016

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Clinical Epigenetics

  • ISSN

    1868-7083

  • e-ISSN

  • Volume of the periodical

    8

  • Issue of the periodical within the volume

    zima

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    20

  • Pages from-to

  • UT code for WoS article

    000370484600001

  • EID of the result in the Scopus database