Role of actin cytoskeleton at multiple levels of T cell activation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F16%3A00473098" target="_blank" >RIV/68378050:_____/16:00473098 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3934/molsci.2016.4.585" target="_blank" >http://dx.doi.org/10.3934/molsci.2016.4.585</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3934/molsci.2016.4.585" target="_blank" >10.3934/molsci.2016.4.585</a>

Result language
angličtina
Original language name
Role of actin cytoskeleton at multiple levels of T cell activation
Original language description
Actin cytoskeleton is an essential cellular structure that is involved in many physiological aspects, including T cell antigenic responses. In has been proposed that actin modulates biophysical parameters of the antigen recognition, forms a barrier inhibiting spontaneous signaling in resting T cells, facilitates TCR signal transduction, stabilizes contacts between T cells and antigen presenting cells, and contributes to the establishment of the antigen affinity threshold. In this review, we discuss the role of actin cytoskeleton at these particular levels of T cell activation.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Project
<a href="/en/project/GJ16-09208Y" target="_blank" >GJ16-09208Y: T cell receptor signaling and fate decisions made by peripheral T cells in homeostasis and during inflammation</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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