X-ray-based microstructural analysis of hydrogel-based composites for bone tissue engineering
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F17%3A00480347" target="_blank" >RIV/68378050:_____/17:00480347 - isvavai.cz</a>
Alternative codes found
RIV/68378297:_____/17:00480347
Result on the web
<a href="http://icmt25.com/e_files/content/Preliminary_BookOfAbstracts_25ICM&T.pdf" target="_blank" >http://icmt25.com/e_files/content/Preliminary_BookOfAbstracts_25ICM&T.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
X-ray-based microstructural analysis of hydrogel-based composites for bone tissue engineering
Original language description
Artificial bone structures implantation becomes a promising treatment procedure in regenerative medicine. To ensure proper function of the scaffold its structural, mechanical and permeability properties have to be investigated and optimized. This study is focused on biodegradable hydrogel gellan gum (GG) reinforced by bioactive glass (BAG) nanoparticles with 0, 50 and 70 wt.%. The samples were subjected to tomografic imaging to obtain detail information about the internal microstructure and BAG particles distribution. As a comparative measurement planar energydispersive X-ray spectroscopy using scanning electron microscope and nanoindentation measurement were performed. The microtomography inspection was performed using the patented (European patent no. EP2835631) in-house designed modular radiographic imaging device equipped with scintillators, large single photon counting and spectroscopic detectors. From reconstructed volumetric data internal microarchitecture, porosity, cell-wall thickness and BAG distribution were derived. The results were compared with the results of the planar analysis of thin scaffold layers prepared by cryosection.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů