Time-lapse micro-tomography analysis of the deformation response of a gellan-gum-based scaffold

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378297%3A_____%2F17%3A00475979" target="_blank" >RIV/68378297:_____/17:00475979 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21260/17:00312315

Result on the web

<a href="http://mit.imt.si/Revija/izvodi/mit173/kytyr.pdf" target="_blank" >http://mit.imt.si/Revija/izvodi/mit173/kytyr.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.17222/mit.2015.237" target="_blank" >10.17222/mit.2015.237</a>

Result language

angličtina

Original language name

Time-lapse micro-tomography analysis of the deformation response of a gellan-gum-based scaffold

Original language description

The presented work is aimed at a demonstration of modern radiological methods for an investigation of the deformation behaviour of bone scaffolds. Bone scaffold is an artificial structure used for the repairs of trabecular bones damaged by injuries or degenerative diseases. In bone-tissue engineering a proper description of its deformation behaviour is one of the most important characteristics for an assessment of the biocompatibility and bone-integration characteristics of the proposed structure intended to be used as a bone scaffold. According to recent studies bioactive-glass-reinforced gellan-gum (GG-BAG) is a promising material for bone-scaffold production. However, its low specific stiffness and simultaneous low attenuation to X-rays makes both the mechanical and imaging parts of the deformation experiments difficult. As a result a state-of-the-art experimental setup composed of high-precision micro-loading apparatus designed for the X-ray observation of deformation processes and an advanced radiographical device is required for such experiments. Furthermore, the radiographical device has to utilize highly sensitive detectors and corresponding radiation sources with appropriate beam characteristics that provide a high signal-to-noise ratio (SNR) during all the measurements. High-resolution time-lapse micro-focus X-ray computed tomography (micro CT) under loading in three different imaging modes was performed to obtain a precise structural and mechanical description of the observed deforming GG-BAG scaffolds. The digital volumetric correlation (DVC) method was applied on reconstructed data from micro CT measurements to evaluate not only the effective mechanical characteristics but also to enable a detailed inspection of the specimens’ internal structure, particularly the deformation modes of the individual struts and joints.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

20501 - Materials engineering

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Materials and Technology

ISSN

1580-2949

e-ISSN

—

Volume of the periodical

51

Issue of the periodical within the volume

3

Country of publishing house

SI - SLOVENIA

Number of pages

6

Pages from-to

397-402

UT code for WoS article

000404817900006

EID of the result in the Scopus database

2-s2.0-85020697472