Mammalian zygotic genome activation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F18%3A00502388" target="_blank" >RIV/68378050:_____/18:00502388 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.semcdb.2017.12.006" target="_blank" >http://dx.doi.org/10.1016/j.semcdb.2017.12.006</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.semcdb.2017.12.006" target="_blank" >10.1016/j.semcdb.2017.12.006</a>

Result language
angličtina
Original language name
Mammalian zygotic genome activation
Original language description
Zygotic genome activation (ZGA) denotes the initiation of gene expression after fertilization. It is part of the complex oocyte-to-embryo transition (OET) in which a highly specialized cell the oocyte is fertilized and transformed into a zygote that gives rise to an embryo that will develop into a newborn. From the perspective of gene expression, the OET reflects reprogramming of germ cell gene expression into the new developmental program of the zygote. This reprogramming occurs at transcriptional and post transcriptional levels. This review will discuss selected aspects of mammalian ZGA, highlighting shared features and evolved differences observed in commonly investigated mammals and non-mammalian model animals. (C) 2017 Elsevier Ltd. All rights reserved.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10604 - Reproductive biology (medical aspects to be 3)

Project
<a href="/en/project/LO1419" target="_blank" >LO1419: Biomodels for Health - Center for model organisms</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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