Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F20%3A00538166" target="_blank" >RIV/68378050:_____/20:00538166 - isvavai.cz</a>

Result on the web

<a href="https://www.nature.com/articles/s41467-019-14069-2" target="_blank" >https://www.nature.com/articles/s41467-019-14069-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41467-019-14069-2" target="_blank" >10.1038/s41467-019-14069-2</a>

Result language

angličtina

Original language name

Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice

Original language description

Brown adipose thermogenesis increases energy expenditure and relies on uncoupling protein 1 (UCP1), however, UCP1 knock-out mice show resistance to diet-induced obesity at room temperature. Here, the authors show that this resistance relies on FGF21-signaling, inducing the browning of white adipose tissue.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nature Communications

ISSN

2041-1723

e-ISSN

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Volume of the periodical

11

Issue of the periodical within the volume

1

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

624

UT code for WoS article

000513245600012

EID of the result in the Scopus database

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