CHICKEN DDNTFR23 AS A CANDIDATE RECEPTOR FOR AN ALV-F SUBGROUP

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F22%3A00567919" target="_blank" >RIV/68378050:_____/22:00567919 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/37/67" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/37/67</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
CHICKEN DDNTFR23 AS A CANDIDATE RECEPTOR FOR AN ALV-F SUBGROUP
Original language description
Avian leukosis virus subgroups (ALV) A, B, C, D, E, J, and K are grouped according to their antigenic reactivity, superinfection interference, and cell receptor usage. However, these characteristics remain to be determined for the endogenous F subgroup. Therefore, we characterized the cell receptor usage for the F subgroup. We constructed arecombinant avian leukosis virus with the F subgroup envgene that replicates only in chicken cells. The F subgroup did not share the cell receptor usage with any other described ALV subgroup by the superinfection interference. We identifiedDDTNFR23 protein as the receptor in chicken and pheasant cells for the F subgroup by an infection of chicken/hamster radiation hybrids. Taken together, we provide amolecular characterization of the F subgroup avian leukosis virus and enhance our knowledge of receptor usage diversification within a closely related virus.
Czech name
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Czech description
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Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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