Osteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F15%3A00443425" target="_blank" >RIV/68378271:_____/15:00443425 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/15:00443425
Result on the web
<a href="http://dx.doi.org/10.2147/IJN.S73628" target="_blank" >http://dx.doi.org/10.2147/IJN.S73628</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/IJN.S73628" target="_blank" >10.2147/IJN.S73628</a>
Alternative languages
Result language
angličtina
Original language name
Osteogenic cell differentiation on H-terminated and O-terminated nanocrystalline diamond films
Original language description
O-terminated NCD films, which are hydrophilic, enhance the adhesion, growth, and osteogenic cell differentiation of Saos-2 cells. This effect is manifested by higher deposition and maturation of collagen I, higher activity of alkaline phosphatase, and higher matrix mineralization on O-terminated NCD films than on H-terminated NCD films, which are hydrophobic. The expression of the genes for collagen I, ALP, and osteocalcin in cells on O-terminated surfaces was similar to or even lower than the expression in cells on H-terminated surfaces. This can be explained by a higher retention of mineralized matrix on O-terminated surfaces than on H-terminated surfaces. Thus, O-terminated NCD films are promising materials for coating bone implants in order to enhace their osseointegration and secondary stability
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EI - Biotechnology and bionics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Nanomedicine
ISSN
1178-2013
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
2015
Country of publishing house
NZ - NEW ZEALAND
Number of pages
16
Pages from-to
869-884
UT code for WoS article
000348439100002
EID of the result in the Scopus database
2-s2.0-84921944545