Highly efficient mesenchymal stem cell proliferation on poly-epsilon-caprolactone nanofibers with embedded magnetic nanoparticles

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F15%3A00454781" target="_blank" >RIV/68378271:_____/15:00454781 - isvavai.cz</a>

Alternative codes found

RIV/68378041:_____/15:00454781

Result on the web

<a href="http://dx.doi.org/10.2147/IJN.S93670" target="_blank" >http://dx.doi.org/10.2147/IJN.S93670</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/IJN.S93670" target="_blank" >10.2147/IJN.S93670</a>

Result language

angličtina

Original language name

Highly efficient mesenchymal stem cell proliferation on poly-epsilon-caprolactone nanofibers with embedded magnetic nanoparticles

Original language description

In this study, we have developed a combined approach to accelerate the proliferation of mesenchymal stem cells in vitro, using a new nanofibrous scaffold made from a mixture of poly-?-caprolactone and magnetic particles. The biological characteristics ofporcine mesenchymal stem cells were investigated while cultured in vitro on composite scaffold enriched with magnetic nanoparticles. Our data indicate that due to the synergic effect of the poly-?-caprolactone nanofibers and magnetic particles, cellularadhesion and proliferation of MSCs is enhanced and osteogenic differentiation is supported. The cellular and physical attributes make this new scaffold very promising for acceleration of efficient mesenchymal stem cell proliferation and regeneration ofhard tissues.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BM - Solid-state physics and magnetism

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Nanomedicine

ISSN

1176-9114

e-ISSN

—

Volume of the periodical

10

Issue of the periodical within the volume

2015

Country of publishing house

NZ - NEW ZEALAND

Number of pages

11

Pages from-to

7307-7317

UT code for WoS article

000366552100001

EID of the result in the Scopus database

2-s2.0-84949870718