Highly efficient mesenchymal stem cell proliferation on poly-epsilon-caprolactone nanofibers with embedded magnetic nanoparticles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F15%3A10315687" target="_blank" >RIV/00216208:11130/15:10315687 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21720/15:00240399 RIV/68407700:21460/15:00240399 RIV/62157124:16170/15:43873661
Result on the web
<a href="http://dx.doi.org/10.2147/IJN.S93670" target="_blank" >http://dx.doi.org/10.2147/IJN.S93670</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2147/IJN.S93670" target="_blank" >10.2147/IJN.S93670</a>
Alternative languages
Result language
angličtina
Original language name
Highly efficient mesenchymal stem cell proliferation on poly-epsilon-caprolactone nanofibers with embedded magnetic nanoparticles
Original language description
In this study, we have developed a combined approach to accelerate the proliferation of mesenchymal stem cells (MSCs) in vitro, using a new nanofibrous scaffold made by needleless electrospinning from a mixture of poly-epsilon-caprolactone and magnetic particles. The biological characteristics of porcine MSCs were investigated while cultured in vitro on composite scaffold enriched with magnetic nanoparticles. Our data indicate that due to the synergic effect of the poly-epsilon-caprolactone nanofibers and magnetic particles, cellular adhesion and proliferation of MSCs is enhanced and osteogenic differentiation is supported. The cellular and physical attributes make this new scaffold very promising for the acceleration of efficient MSC proliferation and regeneration of hard tissues.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EI - Biotechnology and bionics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International journal of nanomedicine [online]
ISSN
1178-2013
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
Prosinec
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
7307-7317
UT code for WoS article
000366552100001
EID of the result in the Scopus database
2-s2.0-84949870718