Synthesis, spectral characterization, structural studies, molecular docking and antimicrobial evaluation of new dioxidouranium(VI) complexes incorporating tetradentate N2O2 Schiff base ligands

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F15%3A00455936" target="_blank" >RIV/68378271:_____/15:00455936 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1039/c5ra17524k" target="_blank" >http://dx.doi.org/10.1039/c5ra17524k</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c5ra17524k" target="_blank" >10.1039/c5ra17524k</a>

Result language
angličtina
Original language name
Synthesis, spectral characterization, structural studies, molecular docking and antimicrobial evaluation of new dioxidouranium(VI) complexes incorporating tetradentate N2O2 Schiff base ligands
Original language description
Two new uranyl(VI) Schiff base complexes [UO2(L1)(DMSO)] (1), where L1 = N,N?-di(5-bromosalicylidene)-1,2-cyclohexyldiaminate ligand and [UO2(L2)(MeOH)] (2), where L2 = N,N?-di(5-bromosalicylidene)-ophenylenediaminate ligand, were synthesized and characterized by elemental analysis, 1H NMR, FTIR, UV-vis, fluorescence spectroscopy and molar conductivity measurements. The structure of the H2L1 free ligand and both complexes (1) and (2) were also determined by single crystal X-ray diffraction. The antimicrobial activity of ligands and complexes was screened against Gram positive bacteria and mol ecular docking of GlcN-6-P synthase with the synthesized compounds was also performed. According to the results, complex 2 displayed minimum binding energy and can be considered as a good antimicrobial agent.n
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BM - Solid-state physics and magnetism
OECD FORD branch
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Project
<a href="/en/project/GA14-03276S" target="_blank" >GA14-03276S: Aspherical effects and their application for statistically correct crystal structure analysis</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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