Synthesis, characterization, crystal structures, QSAR study and antibacterial activities of organotin bisphosphoramidates

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F16%3A00462124" target="_blank" >RIV/68378271:_____/16:00462124 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jorganchem.2015.09.030" target="_blank" >http://dx.doi.org/10.1016/j.jorganchem.2015.09.030</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jorganchem.2015.09.030" target="_blank" >10.1016/j.jorganchem.2015.09.030</a>

Result language
angličtina
Original language name
Synthesis, characterization, crystal structures, QSAR study and antibacterial activities of organotin bisphosphoramidates
Original language description
Organotin complexes of bisphosphoramidates were prepared by the reaction of SnR1R2R3Cl (where R = alkyl/aryl/Cl) and Ph2P(O)XP(O)Ph2 ligands (where X = diamine). All the compounds were characterized by NMR and IR spectroscopy and X-Ray crystallography. The synthesized compounds were screened for the antibacterial activity against B. cereus and E. coli. Triphenyltin adducts exhibited a marked activity only against Gram-positive bacterium B. Cereus. The correlation matrix of QSAR models and docking analysis confirmed the influence of the net charge (QSn) and polarizability of Sn atom of complexes o n the inhibition of B. cereus.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BM - Solid-state physics and magnetism
OECD FORD branch
—

Project
<a href="/en/project/GA15-12653S" target="_blank" >GA15-12653S: Validation and Interpretation of Modulated Structures</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)