Antimicrobial activity of aroylhydrazone-based oxido vanadium(v) complexes: in vitro and in silico studies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F16%3A00465107" target="_blank" >RIV/68378271:_____/16:00465107 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1039/c5nj02594j" target="_blank" >http://dx.doi.org/10.1039/c5nj02594j</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c5nj02594j" target="_blank" >10.1039/c5nj02594j</a>

Result language
angličtina
Original language name
Antimicrobial activity of aroylhydrazone-based oxido vanadium(v) complexes: in vitro and in silico studies
Original language description
A tridentate Schiff base ligand ( E)- N 0-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide and its oxido-vanadium(V) complexes with formulae [VO(L)(MeOH)(OMe)] (1), [VO(L)(OEt)] (2), and [VO(L)(OPr)] (3) have been synthesized and fully characterized by physicochemical and spectroscopic methods including elemental analysis, FT-IR, 1H NMR and molar conductivity. Their solid state structures have also been investigated using single crystal X-ray analysis, and their antimicrobial activity also evaluated. The results showed that all three complexes have significant antibacterial activities. In orde r to determine the potential of these complexes as antimicrobial agents, molecular docking of the complexes with GlcN-6-P synthase was also investigated.n
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BM - Solid-state physics and magnetism
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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