Nanofibrous Scaffolds as Promising Cell Carriers for Tissue Engineering
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F16%3A00467210" target="_blank" >RIV/68378271:_____/16:00467210 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/16:00467210
Result on the web
<a href="http://dx.doi.org/10.5772/63707" target="_blank" >http://dx.doi.org/10.5772/63707</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5772/63707" target="_blank" >10.5772/63707</a>
Alternative languages
Result language
angličtina
Original language name
Nanofibrous Scaffolds as Promising Cell Carriers for Tissue Engineering
Original language description
Nanofibers are promising cell carriers for tissue engineering of a variety of tissues and organs in the human organism. They have been experimentally used for reconstruction of tissues of cardiovascular, respiratory, digestive, urinary, nervous and musculoskeletal systems. Nanofibers are also promising for drug and gene delivery, construction of biosensors and biostimulators, and wound dressings. Nanofibers can be created from a wide range of natural polymers or synthetic biostable and biodegradable polymers. For hard tissue engineering, polymeric nanofibers can be reinforced with various ceramic, metal-based or carbon-based nanoparticles, or created directly from hard materials. The nanofibrous scaffolds can be loaded with various bioactive molecules, such as growth, differentiation and angiogenic factors, or funcionalized with ligands for the cell adhesion receptors. This review also includes our experience in skin tissue engineering using nanofibers fabricated from polycaprolactone and its copolymer with polylactide, cellulose acetate, and particularly from polylactide nanofibers modified by plasma activation and fibrin coating. In addition, we studied the interaction of human bone-derived cells with nanofibrous scaffolds loaded with hydroxyapatite or diamond nanoparticles. We also created novel nanofibers based on diamond deposition on a SiO2 template, and tested their effects on the adhesion, viability and growth of human vascular endothelial cells.
Czech name
—
Czech description
—
Classification
Type
C - Chapter in a specialist book
CEP classification
—
OECD FORD branch
30404 - Biomaterials (as related to medical implants, devices, sensors)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Nanofiber Research - Reaching New Heights
ISBN
978-953-51-2528-0
Number of pages of the result
26
Pages from-to
29-54
Number of pages of the book
252
Publisher name
Rijeka
Place of publication
InTech
UT code for WoS chapter
000399645700004