Newsilver complexes with bioactive glycine and nicotinamide molecules – characterization, DNA binding, antimicrobial and anticancer evaluation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F17%3A00479608" target="_blank" >RIV/68378271:_____/17:00479608 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.jinorgbio.2016.12.003" target="_blank" >http://dx.doi.org/10.1016/j.jinorgbio.2016.12.003</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jinorgbio.2016.12.003" target="_blank" >10.1016/j.jinorgbio.2016.12.003</a>

Result language
angličtina
Original language name
Newsilver complexes with bioactive glycine and nicotinamide molecules – characterization, DNA binding, antimicrobial and anticancer evaluation
Original language description
This study introduces a pair of newly synthesized silver complexes, [Ag2(HGly)2]n(NO3)2n (1) and [Ag(Nam)2]NO3•H2O (2) (Gly – glycine, Nam– nicotinamide), that were prepared and characterized by relevant methods in solid state (elemental, spectral, thermal and structural analysis) and their stability in solution was verified by 1H NMR measurements. Moreover, suitable reaction conditions were observed by potentiometry depending on pH in case of binary system Ag-Gly. The binding of the Ag(I) complexes to calf thymus DNA was investigated using electronic absorption, fluorescence and circular di chroism spectrophotometry.n
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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