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Novel scintillating nanocomposite for X-ray induced photodynamic therapy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00504746" target="_blank" >RIV/68378271:_____/19:00504746 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21340/19:00329825 RIV/00216208:11320/19:10404635

  • Result on the web

    <a href="https://doi.org/10.1016/j.radmeas.2018.12.008" target="_blank" >https://doi.org/10.1016/j.radmeas.2018.12.008</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.radmeas.2018.12.008" target="_blank" >10.1016/j.radmeas.2018.12.008</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Novel scintillating nanocomposite for X-ray induced photodynamic therapy

  • Original language description

    We synthesize a novel prospective nanocomposite material for X-ray induced photodynamic therapy. ZnO:Ga core is coated by the SiO2 shell facilitating a functionalization by a photosensitizer, protoporphyrin PpIX layer.By steady-state and time resolved spectroscopy we confirm the presence of energy transfer between the core and the photosensitizer, an essential requirement to induce a cytotoxic effect. Using the commercial chemical probe we also demonstrate the ability of prepared ZnO:Ga@SiO2-PpIX nanocomposite to generate singlet oxygen. Presented results show that this nanocomposite can be considered as a good candidate for potential application in X-ray induced photodynamic therapy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Radiation Measurements

  • ISSN

    1350-4487

  • e-ISSN

  • Volume of the periodical

    121

  • Issue of the periodical within the volume

    Feb

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    5

  • Pages from-to

    13-17

  • UT code for WoS article

    000458223700003

  • EID of the result in the Scopus database

    2-s2.0-85058692941