Bi-Modal nonlinear optical contrast from Si nanoparticles for cancer theranostics
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00507967" target="_blank" >RIV/68378271:_____/19:00507967 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1002/adom.201801728" target="_blank" >https://doi.org/10.1002/adom.201801728</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/adom.201801728" target="_blank" >10.1002/adom.201801728</a>
Alternative languages
Result language
angličtina
Original language name
Bi-Modal nonlinear optical contrast from Si nanoparticles for cancer theranostics
Original language description
Presenting a safe alternative to conventional compound quantum dots and other functional nanostructures, nanosilicon can offer a series of breakthrough hyperthermia‐based therapies under near‐infrared, radiofrequency, ultrasound, etc., excitation, but the size range to sensitize these therapies is typically too large (>10 nm) to enable efficient imaging functionality based on photoluminescence properties of quantum‐confined excitonic states. Here, it is shown that large Si nanoparticles (NPs) are capable of providing two‐photon excited luminescence (TPEL) and second harmonic generation (SHG) responses, much exceeding that of smaller Si NPs, which promises their use as probes for bi‐modal nonlinear optical bioimaging. It is finally demonstrated that the combination of TPEL and SHG channels makes possible efficient tracing of both separated Si NPs and their aggregations in different cell compartments, while the resolution of such an approach is enough to obtain 3D images.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10306 - Optics (including laser optics and quantum optics)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advanced Optical Materials
ISSN
2195-1071
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
13
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
1-8
UT code for WoS article
000474809500001
EID of the result in the Scopus database
2-s2.0-85065168867