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Microfluidic diamond biosensor using NV centre charge state detection

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00518038" target="_blank" >RIV/68378271:_____/19:00518038 - isvavai.cz</a>

  • Alternative codes found

    RIV/68407700:21460/19:00328300

  • Result on the web

    <a href="http://dx.doi.org/10.1007/978-981-10-9023-3_6" target="_blank" >http://dx.doi.org/10.1007/978-981-10-9023-3_6</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-981-10-9023-3_6" target="_blank" >10.1007/978-981-10-9023-3_6</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Microfluidic diamond biosensor using NV centre charge state detection

  • Original language description

    We develop DNA sensors based on charge switching in colour centres in diamond. The presented method allows the combination of luminescence sensor and electrochemical sensor working on the principle of electrochemical impedance spectroscopy (EIS). The structure consists of highly boron doped diamond electrode on which an intrinsic diamond is deposited. This intrinsic layer contains NV colour centres. The device is then embedded in PDMS microfluidic flow cell and covered by a transparent ITO electrode. The switching of the NV centre charge state as a response, on diamond surface termination, is crucial tool for the sensitive charged molecules sensing. We demonstrated high sensitivity of the near surface NV centres on surface charge termination. O- terminated surface results in a preferable NV centre charge state of NV0 or NV−, whereas H- terminated surface leads to non-PL NV+ charge state. By this principle any charged molecule can be detected by a customized surface functionalization.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Result continuities

  • Project

    <a href="/en/project/GA16-16336S" target="_blank" >GA16-16336S: Quantum detection technologies: nanodiamond for sensing in intracellular environment</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    World Congress on Medical Physics and Biomedical Engineering 2018

  • ISBN

    978-981-10-9022-6

  • ISSN

    1680-0737

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    27-31

  • Publisher name

    Springer

  • Place of publication

    Singapore

  • Event location

    Prague

  • Event date

    Jun 3, 2018

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000449744300006