Simple syntheses of new Pegylated trehalose derivatives as a chemical tool for potential evaluation of cryoprotectant effects on cell membrane
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00524783" target="_blank" >RIV/68378271:_____/20:00524783 - isvavai.cz</a>
Result on the web
<a href="http://hdl.handle.net/11104/0309075" target="_blank" >http://hdl.handle.net/11104/0309075</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/molecules25030497" target="_blank" >10.3390/molecules25030497</a>
Alternative languages
Result language
angličtina
Original language name
Simple syntheses of new Pegylated trehalose derivatives as a chemical tool for potential evaluation of cryoprotectant effects on cell membrane
Original language description
In our work, we developed the synthesis of new polyfunctional pegylated trehalose derivatives and evaluated their cryoprotective effect using flow cytometry. We showed that new compounds (modified trehaloses) bound to appropriate extracellular polymeric cryoprotectants could be helpful as a chemical tool for the evaluation of their potential toxic cell membrane influences. Our aim was to form a chemical tool for the evaluation of cryoprotectant cell membrane influences, which are still not easily predicted during the freezing/thawing process. We combined two basic cryoprotectants: polyethyleneglycols (PEGs) and trehalose in the new chemical compounds—pegylated trehalose hybrids. n
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecules
ISSN
1420-3049
e-ISSN
—
Volume of the periodical
25
Issue of the periodical within the volume
3
Country of publishing house
CH - SWITZERLAND
Number of pages
14
Pages from-to
1-14
UT code for WoS article
000515384800067
EID of the result in the Scopus database
2-s2.0-85078319807