The ε-AlxFe2-xO3 nanomagnets as MRI contrast agents: Factors influencing transverse relaxivity
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00532457" target="_blank" >RIV/68378271:_____/20:00532457 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22340/20:43919634
Result on the web
<a href="https://doi.org/10.1016/j.colsurfa.2020.124423" target="_blank" >https://doi.org/10.1016/j.colsurfa.2020.124423</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.colsurfa.2020.124423" target="_blank" >10.1016/j.colsurfa.2020.124423</a>
Alternative languages
Result language
angličtina
Original language name
The ε-AlxFe2-xO3 nanomagnets as MRI contrast agents: Factors influencing transverse relaxivity
Original language description
Novel type of contrast agents based on non-superparamagnetic nanoparticles of aluminum-doped epsilon polymorph of Fe2O3 is suggested and used as a model system to elucidate the role of magnetic blocking and other factors in the transverse relaxation of water. Specifically, the dependence of the transverse relaxivity r2 on the magnetic field, temperature, magnetization, surface modification and thickness of silica coating is analyzed for the epsilon-AlxFe2-xO3 nanoparticles with x = 0.23 and the median size of 21 nm. Irreversible magnetization processes in aqueous suspension of coated clusters of magnetic crystallites resulted in the field dependence of r2. The temperature dependence of r2 was interpreted by the combination of two different regimes - motional averaging and static dephasing regimes. Moreover, the performance of the contrast agent was demonstrated not only in ultra-high-field MRI at 11.75 T but also by imaging in vivo on a mouse model at 1 T.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Colloids and Surfaces. A - Physicochemical and Engineering Aspects
ISSN
0927-7757
e-ISSN
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Volume of the periodical
589
Issue of the periodical within the volume
Feb
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
11
Pages from-to
1-11
UT code for WoS article
000513861400023
EID of the result in the Scopus database
2-s2.0-85077507452