The synthesis, characterization, DNA/BSA/HSA interactions, molecular modeling, antibacterial properties, andin vitrocytotoxic activities of novel parent and niosome nano-encapsulated Ho(iii) complexes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00533712" target="_blank" >RIV/68378271:_____/20:00533712 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1039/d0ra03436c" target="_blank" >https://doi.org/10.1039/d0ra03436c</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/d0ra03436c" target="_blank" >10.1039/d0ra03436c</a>
Alternative languages
Result language
angličtina
Original language name
The synthesis, characterization, DNA/BSA/HSA interactions, molecular modeling, antibacterial properties, andin vitrocytotoxic activities of novel parent and niosome nano-encapsulated Ho(iii) complexes
Original language description
Based on the importance of metal-centered complexes that can interact with DNA, this research focused on the synthesis of a new Ho(III) complex. This complex was isolated and characterized via elemental analysis, and FT-IR, fluorescence, and UV-vis spectroscopy. Additional confirmation of the Ho(III) complex structure was obtained via single-crystal X-ray diffraction. DNA interaction studies were carried out via circular dichroism (CD) spectroscopy, UV-vis absorption spectroscopy, viscosity measurements and emission spectroscopy. Also, the interactions of this complex with human (HSA) and bovine serum albumin (BSA) proteins were studied via fluorescence spectroscopy techniques and the obtained results reveal an excellent propensity for binding in both cases.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10302 - Condensed matter physics (including formerly solid state physics, supercond.)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
RSC Advances
ISSN
2046-2069
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
39
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
22891-22908
UT code for WoS article
000543298000004
EID of the result in the Scopus database
2-s2.0-85086819979