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The synthesis, characterization, DNA/BSA/HSA interactions, molecular modeling, antibacterial properties, andin vitrocytotoxic activities of novel parent and niosome nano-encapsulated Ho(iii) complexes

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F20%3A00533712" target="_blank" >RIV/68378271:_____/20:00533712 - isvavai.cz</a>

  • Result on the web

    <a href="https://doi.org/10.1039/d0ra03436c" target="_blank" >https://doi.org/10.1039/d0ra03436c</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1039/d0ra03436c" target="_blank" >10.1039/d0ra03436c</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The synthesis, characterization, DNA/BSA/HSA interactions, molecular modeling, antibacterial properties, andin vitrocytotoxic activities of novel parent and niosome nano-encapsulated Ho(iii) complexes

  • Original language description

    Based on the importance of metal-centered complexes that can interact with DNA, this research focused on the synthesis of a new Ho(III) complex. This complex was isolated and characterized via elemental analysis, and FT-IR, fluorescence, and UV-vis spectroscopy. Additional confirmation of the Ho(III) complex structure was obtained via single-crystal X-ray diffraction. DNA interaction studies were carried out via circular dichroism (CD) spectroscopy, UV-vis absorption spectroscopy, viscosity measurements and emission spectroscopy. Also, the interactions of this complex with human (HSA) and bovine serum albumin (BSA) proteins were studied via fluorescence spectroscopy techniques and the obtained results reveal an excellent propensity for binding in both cases.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    RSC Advances

  • ISSN

    2046-2069

  • e-ISSN

  • Volume of the periodical

    10

  • Issue of the periodical within the volume

    39

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    13

  • Pages from-to

    22891-22908

  • UT code for WoS article

    000543298000004

  • EID of the result in the Scopus database

    2-s2.0-85086819979